Polystyrene telechelic polymers are one of the most useful polymers in industrial applications such as serving as compatibilizers and stabilizers in polymer blends and inorganic/organic nanohybrids. This article reviews various synthetic schemes that have been developed in the past decades in producing polystyrene telechelic polymers. Various in-chain end-groups (-NH₂, -COOH, and epoxy group) that are incorporated into the polystyrene macromolecular are discussed. One-pot termination of anionically synthesized living polymers is often used for the synthesis of most polystyrene telechelic polymers with well-defined structure, well-contralled molecular weight and narrow molecular weight distribution. However, such groups as end-amino functionalized polystyrene telechelic polymers are generally prepared using multi-step reactions to obtain high termination efficiency. These synthetic methods have evolved in past the Polystyrene telechelic polymers have gained so much ground in industrial applications that they command attentions from the academia; we are attempting to summarize the development in this area and provide the audience with an overview of the achievements gained in this field.